Alexandra O'neill (Sasha) Duffy, D.O.
Dr. Duffy believes in a strong therapeutic alliance with her patients, staying knowledgeable of contemporary and emerging therapies, and teaching through the care she provides her patients. She is also a wife, mama of two boys and loves to go fly fishing with her family.
Dr. Duffy specializes in movement disorders seeing patients with Parkinson’s disease and atypical parkinsonism, Tremors, Dystonia and Huntington’s disease. She is trained in Deep Brain Stimulation and Botulinum Toxin Injections for treatment of movement disorders.
Dr. Duffy’s research interests are focused on participating in clinical trials in Huntington’s disease. She also dedicates her time as the Neurology Residency Program Director mentoring and teaching the next generation of neurologists.
Guo SY, Duffy AO, Maselli RA, Xiong G. Atypical Case of POEMS Presented as Demyelinating Polyneuropathy With Motor Conduction Block. J Clin Neuromuscul Dis. 2021 Dec 1;23(2):116-118. doi:10.1097/CND.0000000000000385. PMID:34808659.
Simkins TJ, Bissig D, Moreno G, Kahlon NPK, Gorin F, Duffy A. A clinical decision rule predicting outcomes of emergency department patients with altered mental status. J Am Coll Emerg Physicians Open. 2021 Sep 10;2(5):e12522. doi:10.1002/emp2.12522. PMID:34528023.
Wei L, Wang Z, Huang Y, Farias S, Duffy A, Shahlaie K, Wheelock V, Zhang L. A Retrospective Study of Pimavanserin in Patients with Parkinson’s Disease: a Single-center Experience. Neurology. 2021 Apr;96(15 Supplement):2083.
Yee A, Ng K, Park K, Duffy A, Chen D, Simkins T. Chapter 16: Pharmacotherapy for Neurological Conditions. Section: Tremors. Advanced Pharmacology for Prescribers. 2021 Jan. doi:10.1891/9780826195470.
Yuan M, Sperry L, Malhado-Chang N, Duffy A, Wheelock V, Farias S, O'Connor K, Olichney J, Shahlaie K, Zhang L. Atypical antipsychotic therapy in Parkinson's disease psychosis: A retrospective study. Brain Behav. 2017 Apr 14;7(6):e00639. doi:10.1002/brb3.639. PMID:28638698.
Duffy A. Remembering. Neurology. 2016;86;e217. doi:10.1212/WNL.0000000000002692.
Fink KD, Deng P, Gutierrez J, Anderson JS, Torrest A, Komarla A, Kalomoiris S, Cary W, Anderson JD, Gruenloh W, Duffy A, Tempkin T, Annett G, Wheelock V, Segal DJ, Nolta JA. Allele-Specific Reduction of the Mutant Huntingtin Allele Using Transcription Activator-Like Effectors in Human Huntington's Disease Fibroblasts. Cell Transplant. 2016;25(4):677-86. doi:10.3727/096368916X690863. Epub 2016 Feb 4. PMID:26850319.
Pollock K, Dahlenburg H, Nelson H, Fink KD, Cary W, Hendrix K, Annett G, Torrest A, Deng P, Gutierrez J, Nacey C, Pepper K, Kalomoiris S, D Anderson J, McGee J, Gruenloh W, Fury B, Bauer G, Duffy A, Tempkin T, Wheelock V, Nolta JA. Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models. Mol Ther. 2016 May;24(5):965-77. doi:10.1038/mt.2016.12. Epub 2016 Jan 14. PMID:26765769.
Duffy A, Maselli R, Shen P. Case report: Pediatric Guillain-Barre syndrome. Am J Neuroradiol. 2014 Apr. http://www.ajnr.org/site/clcor/2014/04-apr.xhtml
Lurvey R, Duffy A, Rothschild J. Management of Lower Urinary Tract Dysfunction in Parkinson’s Disease: A Review of Recent Treatment Options. Curr Bladder Dysfunct Rep. 2014;9(3):214-220. doi:10.1007/s11884-014-0243-x.